Another device from the “simple” department, today Logitech unveils their Harmony 300 Remote replacing the clutter from your coffee table.   I don’t know if it will be easy enough for grandma to configure, but the Harmony 300 does use a web-based setup that supports over 225,000 devices – even to control your iPod in a dock with IR sensor.

The remote will replace up to four other remotes to get you watching TV with just the press of one button.  Shipping in the U.S. and Europe next month, it will sell for $49.99.